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Anion Gap Calculator

Calculate anion gap for acid-base balance assessment and metabolic disorder diagnosis

最后更新:
阴离子间隙计算
Enter serum electrolyte values to 计算 anion gap

Enable advanced calculation features including Delta间隙, 白蛋白校正AG, and Delta比率 分析

公式

AG = Na+ - (Cl- + HCO3-)

正常范围: 8-16 mEq/L

医学提醒

重要提示

This 计算器 is for 参考 by medical professionals only and cannot replace professional medical diagnosis and treatment.

医学咨询

If anion gap is abnormal, please consult a doctor promptly for further examination and treatment.

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Anion gap formulas
The anion gap estimates the difference between routinely measured serum cations and anions. Albumin correction is included because low albumin can lower the observed gap.
Standard AG = Na+ - (Cl- + HCO3-)
Extended AG = (Na+ + K+) - (Cl- + HCO3-)
Albumin-corrected AG = AG + 2.5 x (4.0 - albumin g/dL)
Na+
Serum sodium
Measured in mmol/L or mEq/L.
Cl-
Serum chloride
Measured in mmol/L or mEq/L.
HCO3-
Serum bicarbonate
Measured in mmol/L or mEq/L.
K+
Serum potassium
Optional in the extended formula.
albumin
Serum albumin
Used for optional correction when available.
How this anion gap calculator works
This tool performs electrolyte arithmetic and presents common interpretation ranges. It cannot diagnose the cause of an acid-base disorder.
  1. Validate that the required electrolytes are present and in plausible numeric ranges.
  2. Calculate the selected standard or potassium-inclusive anion gap formula.
  3. If albumin is provided, apply the common correction of 2.5 mmol/L for every 1 g/dL albumin below 4.0 g/dL.
  4. Compare the result with broad reference ranges and show advanced delta calculations when available.

Important notes

  • Reference intervals vary by lab method, albumin level, patient population, and local reporting conventions.
  • The result should be interpreted with pH, pCO2, lactate, ketones, renal function, medication history, and the full clinical picture.
  • Urgent symptoms, severe electrolyte abnormalities, or suspected toxic ingestion require immediate professional care.

Medical Disclaimer

This tool is for educational purposes only and should not be used as a substitute for professional medical diagnosis or advice.